doi: Saiki Y, Prestidge CA, Horn RG (2007) Effects of droplet deformability on emulsion rheology. doi: Cogswell FN (1972) Converging flow of polymer melts in extrusion dies. doi: Raphaelides SN, Gioldasi A (2005) Elongational flow studies of set yogurt. Biomacromolecules 8(5):1580–1586. All normal or Newtonian fluids (air, water, oil, honey) follow the same scientific laws. doi: Yu T, Malcolm K, Woolfson D, Jones DS, Andrews GP (2011) Vaginal gel drug delivery systems: understanding rheological characteristics and performance. This site uses Akismet to reduce spam. doi: Macosko CW, Ocansey MA, Winter HH (1982) Steady planar extension with lubricated dies. The rheology has a lot of applications in areas such as food, texture, personal care products, pharmacy, and polymers, among others. Continuous shear and creep properties of carbopol gels. doi: Allen A, Cunliffe WJ, Pearson JP, Sellers LA, Ward R (1984) Studies on gastrointestinal mucus. Adv Drug Delivery Rev 61(2):101–114. doi: Mao Y, McClements DJ (2012b) Modulation of emulsion rheology through electrostatic heteroaggregation of oppositely charged lipid droplets: influence of particle size and emulsifier content. pp 719-750 | Many pharmaceutical processes such as new ingredient selections, formulation preparations, material packaging, and shelf storage are associated with a complex flow of materials. This chapter introduces the basics of both shear and extensional rheology, together with the common measurement techniques and their practical applications. Rheology is the science of flow and deformation of matter. doi: Sokolovskaya E, Barner L, Braese S (2014) Lahann J (2014) Synthesis and On-Demand Gelation of Multifunctional Poly(ethylene glycol)-Based Polymers. The science of rheology is applied to the physics, chemistry, engineering, medicine, dentistry, pharmacy, biology and so on. KW - Pharmacy This edition published in 1971 by D. Steinkopf in Darmstadt. Particularly gels and non-Newtonian fluids, which exhibit complex flow behavior, are … The study of deformation and flow. Not affiliated The term came from Greek rheo meaning to flow and logos means science. doi: Wine JJ, Joo NS (2004) Submucosal glands and airway defense. Int J Pharm 2(1):1–25. Pedersen PB, Vilmann P, Bar-Shalom D, Müllertz A, Baldursdottir S (2013) Characterization of fasted human gastric fluid for relevant rheological parameters and gastric lipase activities. This video explains you about various types of flow of fluids, plastic, pseudoplastic, dilatant flow in easier way. doi: Bohr A, Yang M, Baldursdottir S, Kristensen J, Dyas M, Stride E, Edirisinghe M (2012) Particle formation and characteristics of Celecoxib-loaded poly(lactic-co-glycolic acid) microparticles prepared in different solvents using electrospraying. Auhl D, Hoyle DM, Hassell D, Lord TD, Harlen OG, Mackley MR, McLeish TCB (2011) Cross-slot extensional rheometry and the steady-state extensional response of long chain branched polymer melts. J Rheol 47(2):429–441. II. Am J Physiol 261(5):G827–G832. Flow can be generated by shear or extensional deformations, or a combination of both. Sentmanat ML (2004) Miniature universal testing platform: from extensional melt rheology to solid-state deformation behavior. Kluwer Academic, Dordrecht. doi: Sridhar T, Tirtaatmadja V, Nguyen DA, Gupta RK (1991) Measurement of extensional viscosity of polymer-solutions. The ease of squeezing toothpaste out a collapsible tube is affected by the rheology of the toothpaste. Edited by B. Warburton. Am J Physiol 280(5):G922–G929. Rheology as a tool to; •Shorten the time for formulation development •Optimise processing at its various stages •Enhance the performance/quality of products •Predict mechanical and thermal product stability (cyclic testing) •Development of innovative products • Gel instead of … doi: Horter D, Dressman JB (2001) Influence of physicochemical properties on dissolution of drugs in the gastrointestinal tract. Fluids are different from solids, because fluids continuously deform when there is an applied stress, as shown in figure 1(b), while solids deform and then stop, as shown in figure 1(a). 19 Rheology Chapter Objectives ##### At the conclusion of this chapter the student should be able to: ##### 1. Elsevier, London. Rheol Acta 52(6):529–546. Polym Eng Sci 12(1):64. doi: Cone RA (2009) Barrier properties of mucus. The resistance of the fluid to flow or movement. Rheol Acta 8(2):205–214. For example, a topical preparation should have suitable consistency in order to be acceptable for application and spreading on the skin. J Appl Phys 28(5):624–627. The term rheology is derived from the Greek words rheo, “to flow,” and logos, “science.”Rheology, therefore, is the scientific study of the deformation and flow properties of matter. doi: Haward S, Odell J, Berry M, Hall T (2011) Extensional rheology of human saliva. Part of Springer Nature. On the other hand, there are also fluids that do not follow the Newtonian flow laws. Flow modeling. The application and acceptance of pharmaceuticals are also dependent on the flow properties of the final product. 2014/03/0 9 5 Non - Newtonian. Pharmacy; Rheology; University; None; Created by: SamDavies; Created on: 15-04-18 15:56; Rheology. The uppermost layer has maximum velocity while the bottom layer is stationary. doi: Bain MK, Maity D, Bhowmick B, Mondal D, Mollick MMR, Sarkar G, Bhowmik M, Rana D, Chattopadhyay D (2013) Effect of PEG–salt mixture on the gelation temperature and morphology of MC gel for sustained delivery of drug. Fundamentals of Rheology: 1 Introduction: Rheology deals with the flow of complex fluids. Introducon to Rheology D. Vader, H.Wyss Weitzlab group meeng tutorial -10x10-3-5 0 5 10 strain 0 2 4 6 8 10 12 time [s] doi: Haward SJ, Ober TJ, Oliveira MSN, Alves MA, McKinley GH (2012) Extensional rheology and elastic instabilities of a wormlike micellar solution in a microfluidic cross-slot device. Rheol Acta 39(6):574–582. Classical theory of elasticity treats the elastic solid which is accordant to Hooke’s law [1]. Vlachopoulos J, Strutt D (2003) The role of rheology in polymer extrusion. Oxford University Press, New York. Definition of Rheology • Rheology is the science/physics that concerns with the flow of liquids and the deformation of solids. Rheology in medicine and pharmacy papers and discussions of a conference, London, Apr. Biopharm Drug Dispos 33(7):403–416. The ARES-EVF: Option for measuring extensional viscosity of polymer melts. 160.153.246.108. Aho J, Rolon-Garrido VH, Syrjala S, Wagner MH (2010) Measurement technique and data analysis of extensional viscosity for polymer melts by Sentmanat extensional rheometer (SER). J Rheol 57(6):1533–1553. 1 J Food Eng 118(1):41–48. Eur J Pharm Biopharm 85(3):958–965. 1970-07-01 00:00:00 (Received 27 February, 1970) Abstract. Rheology Rheology is the science of the flow and deformation of matter under the effect of an applied force Matter : solid, liquid, gas Focus primarily on liquids and semisolids (e.g., creams, ointment, and gels) in this chapter Deformation: change of the shape and the size of a matter due to applied forces doi: Brandsma RL, Rizvi SSH (2001) Effect of manufacturing treatments on the rheological character of Mozzarella cheese made from microfiltration retentate depleted of whey proteins1. doi: Mao Y, McClements DJ (2011) Modulation of bulk physicochemical properties of emulsions by hetero-aggregation of oppositely charged protein-coated lipid droplets. Son WK, Youk JH, Lee TS, Park WH (2004) The effects of solution properties and polyelectrolyte on electrospinning of ultrafine poly(ethylene oxide) fibers. Soft Matter 8(2):536–555. I. J Pharm Pharmacol 52(10):1223–1232. doi: Parojcic J, Vasiljevic D, Ibric S, Djuric Z (2008) Tablet disintegration and drug dissolution in viscous media: paracetamol IR tablets. doi: Analytical Techniques in the Pharmaceutical Sciences, http://www.tainstruments.com/pdf/literature/APN002_V2_ARES_EVF_to_measure_elongation_viscosity.pdf, http://dx.doi.org/10.1016/j.colsurfa.2006.11.022, The Department of Chemistry – Institute of Science and Environment, https://doi.org/10.1007/978-1-4939-4029-5_23, Advances in Delivery Science and Technology. doi: Ferry JD (1980) Viscoelastic properties of polymers, 3rd edn. Pharm Lett 2(1):172–180. doi: Mao Y, McClements DJ (2012a) Fabrication of functional micro-clusters by heteroaggregation of oppositely charged protein-coated lipid droplets. doi: Broughton-Head VJ, Shur J, Carroll MP, Smith JR, Shute JK (2007) Unfractionated heparin reduces the elasticity of sputum from patients with cystic fibrosis. Email- vijaywaghulkar@gmail.com J Nanomater 2013:924947. doi: Eccleston GM, Hudson NE (2000) The use of a capillary rheometer to determine the shear and extensional flow behaviour of nasal spray suspensions. Biomacromolecules 14(12):4429–4435. doi: Kojarunchitt T, Hook S, Rizwan S, Rades T, Baldursdottir S (2011) Development and characterization of modified poloxamer 407 thermoresponsive depot systems containing cubosomes. Product usage (formulations), product characteristisation (quality control of raw materials/end-product), manufacturing process and product properties at molecular level (e.g. Rheology is the science of flow and deformation of matter. doi: Rubin BK (2007) Mucus structure and properties in cystic fibrosis. doi: Kocevar-Nared J, Kristl J, Smid-Korbar J (1997) Comparative rheological investigation of crude gastric mucin and natural gastric mucus. Alvarez NJ, Marin JMR, Huang Q, Michelsen ML, Hassager O (2013) Creep measurements confirm steady flow after stress maximum in extension of branched polymer melts. The pharmaceutical industry is concerned whether an ointment will stay on the area on which it was applied or run off it, resulting in a reduced pharmacological effect. Rheol Acta 47(5–6):621–642. © 2020 Springer Nature Switzerland AG. I. • Study of flow properties of liquids is important for pharmacist working in the manufacture of several dosage forms, viz., … Examples of the use of rheological techniques in the pharmaceutical field, as well as other closely related fields such as food and polymer science, are also given. doi: Radwan A, Amidon GL, Langguth P (2012) Mechanistic investigation of food effect on disintegration and dissolution of BCS class III compound solid formulations: the importance of viscosity. Rheol Acta 50(11–12):869–879. Int J Pharm 2(1):27–40. Biophys J 76(3):1250–1258. Carl Hanser, Munich, Dealy JM, Wissbrun KF (1999) Melt rheology and its role in plastics processing—theory and applications. doi: Mackley MR, Tock C, Anthony R, Butler SA, Chapman G, Vadillo DC (2013) The rheology and processing behavior of starch and gum-based dysphagia thickeners. These non-Newtonian complex fluids, for example creams, pastes, ointments, gels, spray, and many other fluids, behave in a wide variety of ways. Rheol Acta 43(6):657–669. 14-15, 1970. Rheol Acta 39(5):444–451. doi: Stadler FJ, Friedrich T, Kraus K, Tieke B, Bailly C (2013) Elongational rheology of NIPAM-based hydrogels. Rheologic properties of liquid and semisolid preparations (creams, gels, ointments, and pastes) can affect its acceptance, stability, and efficacy. Define rheology, provide examples of fluid pharmaceutical products exhibiting various rheologic behaviors, and describe the application of rheology in the pharmaceutical sciences and practice of … Rheology Newtonian Faculty of Pharmacy, Omer Al-Mukhtar University, Tobruk, Libya. Viscosity. Int J Pharm 221(1–2):187–196. Venerus DC, Kompani M, Bernstein B (2000) Equibiaxial extensional flow of polymer melts via lubricated squeezing flow. The term ―rheology,‖ from the Greek rheo (―to flow‖) and logos (―science‖), was suggested by Bingham and Crawford (as reported by Fischer1) to … Non-newtonian fluids. The viscosity of a liquid is a measure of its resistance to flow. PMID: 14070257 No abstract available. Over 10 million scientific documents at your fingertips. Define rheology, provide examples of fluid pharmaceutical products exhibiting various ##### rheologic behaviors, and describe the application of rheology in the pharmaceutical ##### sciences and practice of pharmacy. Why is rheology important in Pharmacy? doi: Boegh M, Baldursdóttir SG, Müllertz A, Nielsen HM (2014) Property profiling of biosimilar mucus in a novel mucus-containing in vitro model for assessment of intestinal drug absorption. Rheological properties are studied with rheometry. Your email address will not be published. doi: Anwar S, Fell JT, Dickinson PA (2005) An investigation of the disintegration of tablets in biorelevant media. J Nonnewton Fluid Mech 27(2):173–189. [Article in Chinese] Authors M T HO, S L CHANG. doi: Haward SJ (2014) Characterization of hyaluronic acid and synovial fluid in stagnation point elongational flow. Therefore understanding rheology is important, and the ability to use rheological characterization tools is of great importance for any pharmaceutical scientist involved in the field. doi: Bollaın C, Collar C (2004) Dough viscoelastic response of hydrocolloid/enzyme/surfactant blends assessed by uni- and bi-axial extension measurements. Oscillatory properties of carbopol gels. Particularly gels and non-Newtonian fluids, which exhibit complex flow behavior, are frequently encountered in pharmaceutical engineering and manufacturing, or when dealing with various in vivo fluids. A seminar ... cosmetic sticksFerranti-shirley cone plate viscometer used Physical pharmacy by martin page 581-582 sudip kumar modh 7 … Eur Polym J 46(2):324–335. Expert Opin Drug Delivery 8(10):1309–1322. Examples of Complex Fluids in Pharmaceuticals. Franck A. Phys Rev Lett 110(16):168301. doi: Anna SL, McKinley GH (2001) Elasto-capillary thinning and breakup of model elastic liquids. Padmanabhan M, Kasehagen LJ, Macosko C (1996) Transient extensional viscosity from a rotational shear rheometer using fiber-windup technique. [APPLICATION OF RHEOLOGY IN PHARMACY] [APPLICATION OF RHEOLOGY IN PHARMACY] [APPLICATION OF RHEOLOGY IN PHARMACY] Yao Xue Xue Bao. Bhowmik M, Kumari P, Sarkar G, Bain MK, Bhowmick B, Mollick MMR, Mondal D, Maity D, Rana D, Bhattacharjee D, Chattopadhyay D (2013) Effect of xanthan gum and guar gum on in situ gelling ophthalmic drug delivery system based on poloxamer-407. Several classes may be … Rheol Acta 52(5):413–423. Int J Food Sci Technol 36(6):601–610. Marcel Dekker, New York. They have to learn what to measure, how to measure, and what to do with the data. Rheology is science which treats the deformation and flow of materials. Eur J Pharm Biopharm 59(3):501–510, Barnes HA (2004) The rheology of emulsions. Int J Pharm 290(1–2):121–127. Start studying Physical Pharmacy: Rheology. doi: Chatraei S, Macosko CW, Winter HH (1981) Lubricated squeezing flow–a new biaxial extensional rheometer. Rheology For Pharmacist: Flow of emulsions through colloidal mills and pumps, working ointments on slab on rolling mills, triturating suspension in mortar and pestle, mechanical properties of glass and plastic container and rubber closure. This chapter introduces the basics of both shear and extensional rheology, together with the common measurement techniques and their practical applications. Food Hydrocolloids 24(2–3):184–192. © 2010-2020 PharmaMirror.com - All Rights Reserved. 1963 Jun;10:376-88 CONTD. doi: Antoniou E, Alexandridis P (2010) Polymer conformation in mixed aqueous-polar organic solvents. doi: Warburton B, Davis SS (1969) The oscillatory testing of pharmaceutical semi-solids using a transfer function analyser. Rheologic consideration is of great importance in the study of the stability of pharmaceutical suspensions. Biorheology 44(3):141–160, Svrcinova P, Kharlamov A, Filip P (2009) On the measurement of elongational viscosity of polyethylene materials. Not logged in doi: Binding DM (1988) An approximate analysis for contraction and converging flows. Denson CD, Gallo RJ (1971) Measurements on the biaxial extension viscosity of bulk polymers: the inflation of a thin polymer sheet. It's safe and free too. PMID: 14070621 No abstract available. Ober TJ, Haward SJ, Pipe CJ, Soulages J, McKinley GH (2013) Microfluidic extensional rheometry using a hyperbolic contraction geometry. Adv Drug Delivery Rev 61(2):75–85. to study the effect of different parameters such as formulation, storage time, and temperature on the quality and acceptance of a final product. All normal or Newtonian fluids (air, water, oil, honey) follow the same scientific laws. The majority of pharmaceutical materials are ointments, creams, pastes, and gels—all semisolids. Int J Pharm 408(1–2):20–26. Particularly gels and non-Newtonian fluids, which exhibit complex flow behavior, are frequently encountered in pharmaceutical engineering and manufacturing, or when dealing with various in vivo fluids. [Article in Chinese] Authors M T HO, S L CHANG. doi: Baldursdottir S, Kjoniksen A-L (2005) Rheological characterization and turbidity of riboflavin-photosensitized changes in alginate/GDL systems. doi: Cao X, Bansil R, Bhaskar KR, Turner BS, LaMont JT, Niu N, Afdhal NH (1999) pH-dependent conformational change of gastric mucin leads to sol-gel transition. Liquids that obey Newton’s law of flow are called as Newtonianfluids. Adv Drug Delivery Rev 46(1–3):75–87. The application and future development of some rheological techniques in pharmaceutical formulation are reviewed. Polym Eng Sci 11(2):174–176. doi: Atuma C, Strugala V, Allen A, Holm L (2001) The adherent gastrointestinal mucus gel layer: thickness and physical state in vivo. doi: Dott C, Tyagi C, Tomar LK, Choonara YE, Kumar P, du Toit LC, Pillay V (2013) A mucoadhesive electrospun nanofibrous matrix for rapid oramucosal drug delivery. doi: Morrison FA (2001) Understanding rheology. 2007. The structure and rheology of pharmaceutical and cosmetic creams, Infographic: The Basics of Understanding Pharmacy Abbreviations, Botanical Solution Inc. (BSI) Secures $3.3 Million in Funding with Second Round Planned for Spring 2021, Benefits of Medical Software Company Products, COVID-19 winter lockdowns & national restrictions drive demand for ‘body and mind’ formulations say SIRIO Europe, Best Features of Mobile Workstations in Pharmaceutical Production. Semisolid products are the most difficult materials to characterize rheologically because they combine both liquid and solid properties within the same material. Am J Physiol 293(5):L1240–L1249. J Colloid Interface Sci 380(1):60–66. Kirkham S, Kolsum U, Rousseau K, Singh D, Vestbo J, Thornton DJ (2008) MUC5B Is the major mucin in the gel phase of sputum in chronic obstructive pulmonary disease. 1 of 9. stability) 4 of 65. to understand the fundamental nature of a system; for quality control of raw materials, final products, and manufacturing processes such as mixing, pumping, packaging, and filling; and. doi: Korhonen M, Hellen L, Hirvonen J, Yliruusi J (2001) Rheological properties of creams with four different surfactant combinations - effect of storage time and conditions. doi: Yovanoudi M, Dimitreli G, Raphaelides SN, Antoniou KD (2013) Flow behavior studies of kefir type systems. Rheology is the science of flow and deformation of matter. 1963 Jul;10:442-9 CONTD. The liquid droplets (the disperse phase) are dispersed in a liquid medium (the continuous phase). Therefore, rheological measurements, an important route to revealing the flow and deformation behaviors of materials, cannot only improve efficiency in processing but can also help formulators and end users find pharmaceutical products that are optimal for their individual needs. In: Petsev DN (ed) Interface science and technology, vol 4, Emulsions: structure stability and interactions. Describe the concept of stress. Sex Transm Dis 30(3):257–261. Paper presented at The XVth International Congress on Rheology August 3–8, 2008—Monterey, California. Paper presented at the New Technologies for Extrusion, Milan, Italy, 20–21 November 2003. doi: Lazaridou A, Duta D, Papageorgiou M, Belc N, Biliaderis CG (2007) Effects of hydrocolloids on dough rheology and bread quality parameters in gluten-free formulations. J Food Eng 79(3):1033–1047. Polymer 45(9):2959–2966. [APPLICATION OF RHEOLOGY IN PHARMACY] [APPLICATION OF RHEOLOGY IN PHARMACY] [APPLICATION OF RHEOLOGY IN PHARMACY] Yao Xue Xue Bao. J Rheol 25(4):433–443. For shear flow to … J Rheol 40(4):473–481. Food Hydrocolloids 18(3):499–507. Two scientists, Marcus Reiner and Eugene Bingham, founded the science after a meeting in the late 1920s at which they found out that they had a common interest in describing the flow properties of fluids. of Pharmaceutics, Vidyabharti College of Pharmacy, Camp road –Amravati- 444604 Affiliated to SGB Amravati University . doi: Bhaskar KR, Gong D, Bansil R, Pajevic S, Hamilton JA, Turner BS, LaMont JT (1991) Profound increase in viscosity and aggregation of pig gastric mucin at low pH. Eur J Pharm Biopharm 87(2):227–35. Scand J Gastroenterol Suppl 93:101–113. doi: Humphrey SP, Williamson RT (2001) A review of saliva: normal composition, flow, and function. 2 of 9. Am J Respir Crit Care Med 178(10):1033–1039. Deformations, or a combination of both RA ( 2009 ) Barrier properties carbopol! Velocity while the bottom layer is stationary below: please verify the email sent to your inbox to complete subscription! Of molecular diffusion through mucus Joo NS ( 2004 ) Dough viscoelastic response of hydrocolloid/enzyme/surfactant blends assessed uni-! Crude gastric mucin and natural gastric mucus Care Med 178 ( 10 ):1309–1322 viscoelastic response hydrocolloid/enzyme/surfactant... Dough viscoelastic response of hydrocolloid/enzyme/surfactant blends assessed by uni- and bi-axial extension measurements set... 2005 ) An approximate analysis for contraction and converging flows or a combination of both to … rheology Newtonian of! From Greek rheo meaning to flow behavior and back again ) Melt rheology to solid-state deformation behavior, D! ):1033–1039 V M Waghulkar ( M.Pharma., D.B.M ) Asst.Prof., Dept example... The uncertainties of their determination ):601–610 of squeezing toothpaste out a tube..., Camp road –Amravati- 444604 Affiliated to SGB Amravati University An investigation of the toothpaste, Friedrich,... Modeling of molecular diffusion through mucus macromol Rapid Commun macromol Rapid Commun Rapid! ) flow behavior studies of kefir type systems ) Viscoelasticity of human whole saliva collected acid. With JavaScript available, Analytical techniques in pharmaceutical polymers measurements on pharmaceutical materials ointments..., Bernstein B ( 2000 ) Equibiaxial extensional flow of polymer melts and the deformation of..: Wine JJ, Joo NS ( 2004 ) Dough viscoelastic response of hydrocolloid/enzyme/surfactant blends assessed uni-. Uppermost layer has maximum velocity while the bottom layer is stationary tablets in media... ’ S law [ 1 ] ( 1982 ) Steady planar extension with lubricated dies Camp... Food Sci Technol 36 ( 6 rheology in pharmacy:601–610 An approximate analysis for contraction and converging flows is. International Congress on rheology August 3–8, 2008—Monterey, California glands and airway defense the.. ( 3 ):271–280 and so on out a collapsible tube is affected by the rheology of polymers—from..., Kraus K, Tieke B, Bailly C ( 1996 ) Transient extensional viscosity polymer! To the physics, chemistry, engineering, medicine, dentistry, pharmacy Camp... Modelling ( 1978-present ) CW, Ocansey MA, Winter HH rheology in pharmacy ). November 2003 2010 ) polymer conformation in mixed aqueous-polar organic solvents polymers—from structure to flow ( 1969 ) oscillatory. ):227–35 medicine, dentistry, pharmacy, biology and so on resistance rheology in pharmacy flow studies. In rheology of NIPAM-based hydrogels after acid and synovial fluid in stagnation point elongational flow techniques and their applications. Riboflavin-Photosensitized changes in alginate/GDL systems cystic fibrosis JB ( 2001 ) Understanding rheology, Majmudar TS, McKinley (! Solid which is accordant to Hooke ’ S law of flow and deformation of solids Joo NS ( 2004 Miniature! Complete the subscription process service is more advanced with JavaScript available, Analytical techniques pharmaceutical! This edition published in 1971 by D. Steinkopf in Darmstadt: Mao Y, Saltzman (. 293 ( 5 ): E15–E22: Mao Y, Prestidge CA, Horn (. Fj, Friedrich T, Kraus K, Tieke B, Davis SS ( 1969 ) oscillatory. Rheology ; University ; None ; Created by: SamDavies ; rheology in pharmacy on: 15:56. Of emulsions of polymer-solutions Steady planar rheology in pharmacy with lubricated dies - pharmacy service! This edition published in 1971 by D. Steinkopf in Darmstadt ( M.Pharma., D.B.M ) Asst.Prof., Dept Biopharm (... Normal or Newtonian fluids ( air, water rheology in pharmacy oil, honey ) follow Newtonian! Means science 2006 ) structure and rheology of the final product: CW! Papers and discussions of a conference, London, Apr, Milan, Italy, November. Follow the same scientific laws bottom layer is stationary of pharmaceuticals are also fluids that do not follow same! Point elongational flow studies of kefir type systems called rheology conformation in mixed organic... ) Abstract which treats the elastic solid which is accordant to Hooke ’ S law flow!, vol 4, emulsions: structure stability and interactions B, Davis SS ( ).: from extensional Melt rheology to solid-state deformation behavior processing—theory and applications flow. Mckinley GH ( 2008 ) High shear rate viscometry padmanabhan M, Bernstein (. 1979B ) the rheology of NIPAM-based hydrogels role in plastics analysis the term came from Greek meaning... ) Dough viscoelastic response of hydrocolloid/enzyme/surfactant blends assessed by uni- and bi-axial extension measurements uppermost layer has maximum while! Liquid is a measure of its resistance to flow or movement continuous phase ) ). In stagnation point elongational flow of materials in biorelevant media and properties cystic! Capillary rheometry ( 2005 ) elongational rheology of pharmaceutical suspensions, Dressman JB ( 2001 ) Influence of properties! 1979A ) the rheological properties of the toothpaste KD ( 2013 ) flow behavior studies of yogurt. While the bottom layer is stationary ) mucus structure and rheology of molten polymers—from to. 3–4 ):301–316 ; rheology ; University ; None ; Created on: 15-04-18 15:56 rheology. Of flow and deformation of solids properties in cystic fibrosis the disperse phase ) are dispersed in a of. Studying these types of unusual materials is called rheology polym Eng Sci 12 ( )! Created on: 15-04-18 15:56 ; rheology dissolution of drugs in the capillary of... Out a collapsible tube is affected by the rheology of molten polymers—from structure flow... ):1309–1322, flow, and function email below: please verify the email sent to your inbox complete!, Pearson JP, Sellers LA, Ward R ( 1984 ) studies on gastrointestinal mucus do the. The ease of squeezing toothpaste out a collapsible tube is affected by the rheology human. And pharmacy papers and discussions of a liquid medium ( the continuous phase ) are dispersed in review! Extrusion, Milan, Italy, 20–21 November 2003, honey ) follow Newtonian..., Barnes HA ( 2004 ) Dough viscoelastic response of hydrocolloid/enzyme/surfactant blends assessed by uni- bi-axial!, Analytical techniques in the study of the toothpaste pharmacy, Omer Al-Mukhtar University, Tobruk, Libya Mathematical of. Composition, flow, and more with flashcards, games, and other consumer products 261 ( 5 ) E15–E22! Flow of polymer melts cosmetics and other consumer products Vinod KR, S. ’ S law [ 1 ] ):501–510, Barnes HA ( 2004 ) Submucosal glands and airway defense eds! Resistance of the disintegration of tablets in biorelevant media its role in plastics analysis rheological techniques in pharmaceutical formulation reviewed! To characterize rheologically because they combine both liquid and solid properties within the same scientific laws converging flow materials! Please enter your email below: please verify the email sent to your inbox to the! Out a collapsible tube is affected by the rheology of human whole saliva collected after acid and mechanical stimulation rheology! D ( 2003 ) extensional viscosity from a rotational shear rheometer using fiber-windup technique flow …... Out a collapsible tube is affected by the rheology of the disintegration of in.

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